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HomeUKDrug therapy for cataracts strikes a step nearer – research

Drug therapy for cataracts strikes a step nearer – research



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new therapy may pave the way in which for cataracts to be handled with medication as a substitute of the presently required surgical procedure, new analysis suggests.

Cataracts are when the lens, the small clear disc inside your eye, develops cloudy patches of protein, resulting in imaginative and prescient loss and blindness for tens of millions worldwide.

A crew of worldwide scientists, led by Professor Barbara Pierscionek at Anglia Ruskin College (ARU), have been finishing up superior exams on a compound proposed as an anti-cataract drug.

It’s a vital step ahead in the direction of treating this extraordinarily widespread situation with medication somewhat than surgical procedure

In laboratory trials in mice, therapy with the oxysterol compound VP1-001 was proven to revive protein organisation of the lens, ensuing within the lens being higher in a position to focus.

This was supported by a discount in clouding in 46% of instances.

Researchers say there was a exceptional enchancment in eyes handled with the compound.

They recommend the findings are a big step ahead in the direction of treating the situation with medication as a substitute of surgical procedure.

Professor Pierscionek, who’s deputy dean within the College of Well being, Training, Medication and Social Care at ARU, stated: “This research has proven the optimistic results of a compound that had been proposed as an anti-cataract drug however by no means earlier than examined on the optics of the lens.

“It’s the first analysis of this type on the planet.

“It has proven that there’s a exceptional distinction and enchancment in optics between eyes with the identical kind of cataract that had been handled with the compound in contrast to people who weren’t.

“Enhancements occurred in some sorts of cataract however not in all, indicating that this can be a therapy for particular cataracts.

“This means distinctions could have to be made between cataract varieties when growing anti-cataract medicines.

“It’s a vital step ahead in the direction of treating this extraordinarily widespread situation with medication somewhat than surgical procedure.”

The findings are printed within the journal Investigative Ophthalmology and Visible Science.



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