The DJ, who has been working on the station for 17 years, beforehand mentioned she is leaving the station to spend extra time along with her household.
She informed listeners that she is aware of “that I’ve achieved the best factor as a result of it feels good, I really feel at peace with every little thing”.
She added: “I’m not going, hopefully I’ll get a job on the radio sooner or later sooner or later.
“I would love that and I’m nonetheless going to be doing different issues.
“I’m wanting ahead to having the artistic area to do new issues and check out new issues.
“However being at Radio 1 is such a celebration. I’ve had such sensible instances with the opposite DJs over time, I’ve made mates for all times.”
Mac added there are extra ladies taking part in “different music” than when she joined the station 17 years in the past.
“What’s nice is that now, 17 years later, there’s so many,” she added.
Mac additionally credited Radio 1 with enabling her to get to know her now husband Toddla T.
“I began on Radio 1 in 2004 and have achieved a whole lot of issues since then in my skilled life and private life,” she mentioned.
“A kind of was getting married and changing into a mom to 2 youngsters, and it was due to Radio 1 that I received to know my husband a bit of bit higher.”
She mentioned that after assembly the DJ in a nightclub “I invited him on to the present to do a little bit of an interview”.
The pair have been residing collectively round a 12 months later, she added.
Clara Amfo is taking up her Future Sounds present.
Her fellow Radio 1 DJ Scott Mills praised Mac on her last day.
“Feeling emotional listening to @anniemacmanus Annie you’re the BEST get @BBCR1 on NOW,” he tweeted.
Nick Grimshaw, one other Radio 1 DJ, added: “not me crying to Excessive Distinction @anniemacmanus BBCR1 LETS DO THIS GUYS!!!! THE LAST FRIDAY WITH ANNIE.”