The well being employees, who’re understood to each have a historical past of extreme allergic reactions, had been amongst hundreds to obtain the vaccine on the primary day of the Covid-19 mass vaccination programme.
In response Dr June Raine, chief govt of the Medicines and Healthcare merchandise Regulatory Company (MHRA), instructed folks with a historical past of life-threatening allergic reactions to a vaccine or meals to not get the Pfizer Covid-19 jab
Nonetheless, Professor David Salisbury, a former Division of Well being director of immunisation, stated that opposed reactions occur “of the order of about one in one million doses”.
“Extreme opposed reactions, allergic ones to vaccines, do occur however they’re very uncommon,” he instructed BBC Radio 4’s As we speak programme.
“They occur of the order of about one in one million doses. And all people who administers vaccines on this nation is skilled to cope with them.”
Dr Raine stated a bunch together with consultants on allergy and scientific immunology was convened on Wednesday to think about any attainable mitigation to the “uncommon danger of anaphylaxis”.
She stated: “Any individual with a historical past of anaphylaxis to a vaccine, medication or meals mustn’t obtain the Pfizer BioNTech vaccine. A second dose shouldn’t be given to anybody who has skilled anaphylaxis following administration of the primary dose of this vaccine.
“Anaphylaxis is a identified, though very uncommon, facet impact with any vaccine. Most individuals is not going to get anaphylaxis and the advantages in defending folks towards Covid-19 outweigh the dangers.”
Pfizer stated the vaccine was “nicely tolerated” through the trials with “no severe security considerations”.
Dr Raine added: “You could be fully assured that this vaccine has met the MHRA’s sturdy requirements of security, high quality and effectiveness.
“The security information has additionally been critically assessed by the federal government’s impartial advisory physique, the Fee on Human Medicines. No vaccine could be permitted until it meets these stringent requirements – on that you may make certain.”